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Issue:ISSN 1000-7083
          CN 51-1193/Q
Director:Sichuan Association for Science and Technology
Sponsored by:Sichuan Society of Zoologists; Chengdu Giant Panda Breeding Research Foundation; Sichuan Association of Wildlife Conservation; Sichuan University
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Your Position :Home->Past Journals Catalog->2013 Vol.32 No.2

Advance in Studies of Lysozyme in Ruminant
Author of the article:ZHANG Peng1,2, JIANG Mingfeng 1,2, WANG Yong1*
Author's Workplace:(1.Key Laboratory of Sichuan Province for Qinghai-Tibetan Plateau Animal Genetic Resource Reservation and Exploitation, Chengdu 610041, China; 2. College of Life Science and Technology, Southwest University for Nationalities, Chengdu 610041, China)
Key Words:ruminant; lysozyme; acid resistance; enzymological characteristics; molecular evolution
Abstract:At present, the side effect caused by misuse of antibiotic becomes more and more serious, seeking effective alternatives for antibiotics is particularly urgent. Lysozyme is able to catalyze the hydrolysis of β-1,4-glycosidic bonds between the N-acetylglucosamine and N-acetylmuramic acid in the peptidoglycan layer of bacterial cell walls. It functions as bacteria digestion and decomposition, and exogenous microbial growth inhibition, and immunity enhancement. Lysozyme is widespread in animals especially in the ruminant in vivo. In this paper, we summarized recent research progresses on lysozyme with the focus on origin and distribution, gene sequence, protein structure and the enzymological characteristics, the biological functions and activities of lysozymes, and discussed its acid resistance. Meanwhile, the evolution of lysozyme in ruminant was also discussed. Finally, we suggested perspectives of lysozyme. It’s very significant to research the lysozyme in ruminant for its underlying role to understand the basic knowledge and to probably application in the production.
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